Molecular weight (DA)
45kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RASSF6. AA range:129-178
Specificity
RASSF6 Polyclonal Antibody detects endogenous levels of RASSF6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012],
Function
function:May act as a Ras effector protein.,sequence caution:Translated as Gln.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,
Protein name
Ras association domain-containing protein 6
Other name
RASSF6; Ras association domain-containing protein 6
Fields
>>Hippo signaling pathway;>>Hippo signaling pathway - multiple species
Human protein sequence Database
Q6ZTQ3
Mouse protein sequence database
Q80UQ2
Rat protein sequence database
Tissue expression
Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车