Molecular weight (DA)
29kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB34. AA range:206-255
Specificity
Rab 34 Polyclonal Antibody detects endogenous levels of Rab 34 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000.IHC-p 1:50-200 ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012],
Function
function:Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Associates with the Golgi complex.,subunit:Interacts with RILP.,
Protein name
Ras-related protein Rab-34
Other name
RAB34; RAB39; RAH; Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah
Human protein sequence Database
Q9BZG1
Mouse protein sequence database
Q64008
Rat protein sequence database
Cellular localization
Cytoplasm . Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Cell projection, cilium . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
Tissue expression
Brain,Embryo,Heart,Mammary gland,Pancreas,Skeletal muscle,
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