Molecular weight (DA)
21kD
Immunogen
Synthesized peptide derived from Rab 31 . at AA range: 50-130
Specificity
Rab 31 Polyclonal Antibody detects endogenous levels of Rab 31 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009],
Function
similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.,
Protein name
Ras-related protein Rab-31
Other name
RAB31; RAB22B; Ras-related protein Rab-31; Ras-related protein Rab-22B
Human protein sequence Database
Q13636
Mouse protein sequence database
Q921E2
Rat protein sequence database
Q6GQP4
Cellular localization
Golgi apparatus, trans-Golgi network . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
Tissue expression
Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.
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