Molecular weight (DA)
210kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AS250. AA range:641-690
Specificity
AS250 Polyclonal Antibody detects endogenous levels of AS250 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
RALGAPA2 (Ral GTPase Activating Protein Catalytic Alpha Subunit 2) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Translocation of GLUT4 to the plasma membrane. GO annotations related to this gene include protein heterodimerization activity and GTPase activator activity. An important paralog of this gene is RAP1GAP.
Function
regulation of small GTPase mediated signal transduction,
Protein name
Ral GTPase-activating protein subunit alpha-2
Other name
RALGAPA2; C20orf74; KIAA1272; Ral GTPase-activating protein subunit alpha-2; 250 kDa substrate of Akt; AS250; p220
Fields
>>Ras signaling pathway
Human protein sequence Database
Q2PPJ7
Mouse protein sequence database
A3KGS3
Rat protein sequence database
Cellular localization
Cytoplasm .
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