Molecular weight (DA)
21kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human TDGF1P3. AA range:1-50
Specificity
Cripto-3 Polyclonal Antibody detects endogenous levels of Cripto-3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The TDGF3 locus has characteristics of a retrotransposon, including lack of introns and a poly(A) sequence. [provided by RefSeq, Jul 2008],
Function
function:Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.,similarity:Contains 1 EGF-like domain.,tissue specificity:Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.,
Protein name
Putative teratocarcinoma-derived growth factor 3
Other name
TDGF1P3; CRIPTO3; TDGF2; TDGF3; Putative teratocarcinoma-derived growth factor 3; Cripto-3 growth factor; Epidermal growth factor-like cripto protein CR3; Teratocarcinoma-derived growth factor 1 pseudogene 3
Human protein sequence Database
P51864
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane .
Tissue expression
Expressed weakly in lung, colon and breast. Expressed also strongly in primary cancer tissues; lung and colon cancers.
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