Molecular weight (DA)
57kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ANGPTL1. AA range:11-60
Specificity
Angptl1 Polyclonal Antibody detects endogenous levels of Angptl1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.,
Protein name
Angiopoietin-related protein 1
Other name
ANGPTL1; ANG3; ANGPT3; ARP1; PSEC0154; Angiopoietin-related protein 1; Angiopoietin-3; ANG-3; Angiopoietin-like protein 1
Human protein sequence Database
O95841
Mouse protein sequence database
Q640P2
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.
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