Molecular weight (DA)
20kD
Immunogen
The antiserum was produced against synthesized peptide derived from human VIP. AA range:71-120
Specificity
VIP Polyclonal Antibody detects endogenous levels of VIP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014],
Function
function:PHM and PHV also cause vasodilation.,function:VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.,online information:Vasoactive intestinal peptide entry,similarity:Belongs to the glucagon family.,
Protein name
VIP peptides
Other name
VIP; VIP peptides
Fields
>>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction
Human protein sequence Database
P01282
Mouse protein sequence database
P32648
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Pancreatic carcinoma,Pheochromocytoma,Prostate,
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