Immunogen
The antiserum was produced against synthesized peptide derived from human CKLF1. AA range:120-169
Specificity
CMTM1 Polyclonal Antibody detects endogenous levels of CMTM1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011],
Function
similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in testis.,
Protein name
CKLF-like MARVEL transmembrane domain-containing protein 1
Other name
CMTM1; CKLFSF1; CKLF-like MARVEL transmembrane domain-containing protein 1; Chemokine-like factor superfamily member 1
Human protein sequence Database
Q8IZ96
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Highly expressed in testis.