Molecular weight (DA)
45kD
Immunogen
The antiserum was produced against synthesized peptide derived from human OCT6. AA range:311-360
Specificity
Oct-6 Polyclonal Antibody detects endogenous levels of 40822 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.,similarity:Belongs to the POU transcription factor family. Class-3 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Expressed in embryonal stem cells and in the developing brain.,
Function
function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.,similarity:Belongs to the POU transcription factor family. Class-3 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Expressed in embryonal stem cells and in the developing brain.,
Protein name
POU domain class 3 transcription factor 1
Other name
POU3F1; OCT6; OTF6; POU domain; class 3, transcription factor 1; Octamer-binding protein 6; Oct-6; Octamer-binding transcription factor 6; OTF-6; POU domain transcription factor SCIP
Human protein sequence Database
Q03052
Mouse protein sequence database
P21952
Rat protein sequence database
P20267
Cellular localization
Nucleus .
Tissue expression
Expressed in embryonal stem cells and in the developing brain.
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