Molecular weight (DA)
78kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BCAM. AA range:191-240
Specificity
CD239 Polyclonal Antibody detects endogenous levels of CD239 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
Function
cell adhesion, cell-matrix adhesion, biological adhesion, cell-substrate adhesion,
Protein name
Basal cell adhesion molecule
Other name
BCAM; LU; MSK19; Basal cell adhesion molecule; Auberger B antigen; B-CAM cell surface glycoprotein; F8/G253 antigen; Lutheran antigen; Lutheran blood group glycoprotein; CD239
Human protein sequence Database
P50895
Mouse protein sequence database
Q9R069
Rat protein sequence database
Q9ESS6
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车