Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MRGX3. AA range:99-148
Specificity
MRGX3 Polyclonal Antibody detects endogenous levels of MRGX3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009],
Function
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
Protein name
Mas-related G-protein coupled receptor member X3
Other name
MRGPRX3; MRGX3; SNSR1; SNSR2; Mas-related G-protein coupled receptor member X3; Sensory neuron-specific G-protein coupled receptor 1/2
Human protein sequence Database
Q96LB0
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
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