Molecular weight (DA)
44kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR34. AA range:181-230
Specificity
GPR34 Polyclonal Antibody detects endogenous levels of GPR34 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Broadly expressed.,
Protein name
Probable G-protein coupled receptor 34
Other name
GPR34; Probable G-protein coupled receptor 34
Human protein sequence Database
Q9UPC5
Mouse protein sequence database
Q9R1K6
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Broadly expressed.
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