Molecular weight (DA)
46kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PEVR2. AA range:235-284
Specificity
GPR172B Polyclonal Antibody detects endogenous levels of GPR172B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013],
Function
function:Acts as receptor for porcine endogenous retrovirus subgroup A (PERV-A).,similarity:Belongs to the PERVR family.,tissue specificity:Detected in a wide variety of tissues. High expression in testis.,
Protein name
Solute carrier family 52 riboflavin transporter member 1
Other name
SLC52A1; GPR172B; PAR2; RFT1; Solute carrier family 52; riboflavin transporter, member 1; Porcine endogenous retrovirus A receptor 2; PERV-A receptor 2; Protein GPR172B; Riboflavin transporter 1; hRFT1
Human protein sequence Database
Q9NWF4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.
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