Immunogen
Synthesized peptide derived from Serine racemase . at AA range: 90-170
Specificity
Serine racemase Polyclonal Antibody detects endogenous levels of Serine racemase protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:L-serine = D-serine.,cofactor:Pyridoxal phosphate.,function:Catalyzes the synthesis of D-serine from L-serine.,similarity:Belongs to the serine/threonine dehydratase family.,tissue specificity:Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.,
Function
catalytic activity:L-serine = D-serine.,cofactor:Pyridoxal phosphate.,function:Catalyzes the synthesis of D-serine from L-serine.,similarity:Belongs to the serine/threonine dehydratase family.,tissue specificity:Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.,
Protein name
Serine racemase
Abbreviation
Serine racemase
Other name
SRR; Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase
Fields
>>Glycine, serine and threonine metabolism;>>D-Amino acid metabolism;>>Metabolic pathways
Human protein sequence Database
Q9GZT4
Mouse protein sequence database
Q9QZX7
Rat protein sequence database
Cellular localization
cytoplasm,plasma membrane,neuronal cell body,apical part of cell,
Tissue expression
Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
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