Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CDK5R2. AA range:81-130
Specificity
p39 Polyclonal Antibody detects endogenous levels of p39 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008],
Function
function:Activator of CDK5/TPKII.,similarity:Belongs to the cyclin-dependent kinase 5 activator family.,subunit:Heterodimer of a catalytic subunit and a regulatory subunit.,tissue specificity:Brain and neuron specific.,
Protein name
Cyclin-dependent kinase 5 activator 2
Other name
CDK5R2; NCK5AI; Cyclin-dependent kinase 5 activator 2; CDK5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; p39; p39I
Human protein sequence Database
Q13319
Mouse protein sequence database
O35926
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Tissue expression
Brain and neuron specific.