Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human OMG. AA range:282-331
Specificity
OMG Polyclonal Antibody detects endogenous levels of OMG protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:Do not confuse oligodendrocyte-myelin glycoprotein (OMG) with myelin-oligodendrocyte glycoprotein (MOG).,function:Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.,PTM:O-glycosylated in its Ser/Thr-rich repeat domain .,similarity:Contains 8 LRR (leucine-rich) repeats.,subunit:Binds to RTN4R.,tissue specificity:Oligodendrocytes and myelin of the central nervous system.,
Function
caution:Do not confuse oligodendrocyte-myelin glycoprotein (OMG) with myelin-oligodendrocyte glycoprotein (MOG).,function:Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.,PTM:O-glycosylated in its Ser/Thr-rich repeat domain .,similarity:Contains 8 LRR (leucine-rich) repeats.,subunit:Binds to RTN4R.,tissue specificity:Oligodendrocytes and myelin of the central nervous system.,
Protein name
Oligodendrocyte-myelin glycoprotein
Other name
OMG; OMGP; Oligodendrocyte-myelin glycoprotein
Human protein sequence Database
P23515
Mouse protein sequence database
Q63912
Rat protein sequence database
Cellular localization
Cell membrane; Lipid-anchor, GPI-anchor.
Tissue expression
Oligodendrocytes and myelin of the central nervous system.