Immunogen
Synthesized peptide derived from the C-terminal region of human CASPR3.
Specificity
CASPR3 Polyclonal Antibody detects endogenous levels of CASPR3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the neurexin family.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 fibrinogen C-terminal domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 4 laminin G-like domains.,
Protein name
Contactin-associated protein-like 3
Other name
CNTNAP3; CASPR3; KIAA1714; Contactin-associated protein-like 3; Cell recognition molecule Caspr3
Human protein sequence Database
Q9BZ76
Mouse protein sequence database
Rat protein sequence database
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
Tissue expression
Brain,Human fetal brain,Prostate,
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