Molecular weight (DA)
116kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CARD6. AA range:1-50
Specificity
CARD 6 Polyclonal Antibody detects endogenous levels of CARD 6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008],
Function
function:May be involved in apoptosis.,similarity:Contains 1 CARD domain.,
Protein name
Caspase recruitment domain-containing protein 6
Other name
CARD6; Caspase recruitment domain-containing protein 6
Fields
>>NOD-like receptor signaling pathway
Human protein sequence Database
Q9BX69
Mouse protein sequence database
Rat protein sequence database
Tissue expression
Aorta endothelial cell,Colon,Epithelium,Skeletal muscle,
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