Molecular weight (DA)
61kD
Immunogen
Synthesized peptide derived from human Keratin 77
Specificity
This antibody detects endogenous levels of human Keratin 77
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009],
Function
miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Undergoes deimination of some arginine residues (citrullination).,similarity:Belongs to the intermediate filament family.,tissue specificity:Expressed exclusively in skin.,
Other name
Keratin, type II cytoskeletal 1b (Cytokeratin-1B;CK-1B;Keratin-77;K77;Type-II keratin Kb39)
Human protein sequence Database
Q7Z794
Mouse protein sequence database
Rat protein sequence database
Cellular localization
cytoskeleton,intermediate filament,keratin filament,extracellular exosome,
Tissue expression
Expressed exclusively in skin.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车