Immunogen
Synthetic peptide from human protein at AA range: 81-130
Specificity
The antibody detects endogenous IL-17C
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008],
Function
function:Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,
Gene Name
IL17C UNQ561/PRO1122
Protein name
Interleukin-17C (IL-17C) (Cytokine CX2)
Other name
Interleukin-17C (IL-17C;Cytokine CX2)
Fields
>>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway
Human protein sequence Database
Q9P0M4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
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