Molecular weight (DA)
87kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
YYAP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Function
function:Enhances transcription activation by YY1.,sequence caution:Translated as Tyr.,similarity:Contains 1 Myb-like domain.,similarity:Contains 2 PAH (paired amphipathic helix) repeats.,subunit:Interacts with YY1.,tissue specificity:Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.,
Gene Name
YY1AP1 HCCA2 YY1AP
Protein name
YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2)
Human protein sequence Database
Q9H869
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Nucleus, nucleoplasm . Nucleus, nucleolus .
Tissue expression
Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
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