Molecular weight (DA)
67kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
HIC2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transcriptional repressor.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Interacts with CtBP.,tissue specificity:Highest levels in cerebellum.,
Function
function:Transcriptional repressor.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Interacts with CtBP.,tissue specificity:Highest levels in cerebellum.,
Gene Name
HIC2 HRG22 KIAA1020 ZBTB30
Protein name
Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30)
Human protein sequence Database
Q96JB3
Mouse protein sequence database
Q9JLZ6
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Highest levels in cerebellum.
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