Molecular weight (DA)
15kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
PROF2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008],
Function
function:Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.,similarity:Belongs to the profilin family.,subunit:Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.,tissue specificity:Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.,
Protein name
Profilin-2 (Profilin II)
Fields
>>Rap1 signaling pathway;>>Regulation of actin cytoskeleton;>>Amyotrophic lateral sclerosis;>>Shigellosis;>>Salmonella infection
Human protein sequence Database
P35080
Mouse protein sequence database
Q9JJV2
Rat protein sequence database
Q9EPC6
Cellular localization
Cytoplasm, cytoskeleton.
Tissue expression
Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车