Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TXLNA Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:Was originally (PubMed:8327514) thought to be a high molecular weight interleukin (IL-14 or IL14).,function:May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.,similarity:Belongs to the taxilin family.,subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex.,tissue specificity:Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.,
Function
caution:Was originally (PubMed:8327514) thought to be a high molecular weight interleukin (IL-14 or IL14).,function:May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.,similarity:Belongs to the taxilin family.,subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex.,tissue specificity:Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.,
Protein name
Alpha-taxilin
Human protein sequence Database
P40222
Mouse protein sequence database
Q6PAM1
Rat protein sequence database
Cellular localization
extracellular region,cytoplasm,membrane,
Tissue expression
Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.
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