Molecular weight (DA)
45kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
WDFY1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a phosphatidylinositol 3-phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain. [provided by RefSeq, Jan 2015],
Function
similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 7 WD repeats.,subunit:Binds PtdIns3P in vitro with high specificity over other phosphoinositides.,
Gene Name
WDFY1 KIAA1435 WDF1 ZFYVE17
Protein name
WD repeat and FYVE domain-containing protein 1 (FENS-1) (Phosphoinositide-binding protein 1) (WD40- and FYVE domain-containing protein 1) (Zinc finger FYVE domain-containing protein 17)
Human protein sequence Database
Q8IWB7
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Early endosome .
Tissue expression
Brain,Ovary,Skin,
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