Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
TAAR8 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is part of the trace amine receptor cluster on chromosome 6 and encodes an orphan G-protein coupled receptor. Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain. [provided by RefSeq, Jul 2016],
Function
function:Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested.,
Gene Name
TAAR8 GPR102 TA5 TAR5 TRAR5
Protein name
Trace amine-associated receptor 8 (TaR-8) (Trace amine receptor 8) (G-protein coupled receptor 102) (Trace amine receptor 5) (TaR-5)
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q969N4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested.
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