Molecular weight (DA)
92kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Specificity
TS1R1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
Function
function:Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.,online information:The taste experience -Issue 55 of February 2005,similarity:Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.,subunit:Forms heterodimers with TAS1R3.,
Gene Name
TAS1R1 GPR70 T1R1 TR1 GM148
Protein name
Taste receptor type 1 member 1 (G-protein coupled receptor 70)
Fields
>>Taste transduction
Human protein sequence Database
Q7RTX1
Mouse protein sequence database
Q99PG6
Rat protein sequence database
Q9Z0R8
Cellular localization
Cell membrane; Multi-pass membrane protein.
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