Molecular weight (DA)
52kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 360-440
Specificity
RGDSR Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras-Raf-MEK-ERK cascade. [provided by RefSeq, Jul 2016],
Function
alternative products:A number of isoforms are produced,similarity:Contains 1 Ras-GEF domain.,
Protein name
Ral-GDS-related protein (hRGR) (Ral guanine nucleotide dissociation stimulator-like 4) (RalGDS-like 4)
Human protein sequence Database
Q8IZJ4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasmic vesicle .
Tissue expression
PCR rescued clones,Testis,
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