Molecular weight (DA)
145kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
GP125 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012],
Function
domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,
Gene Name
GPR125 UNQ556/PRO1113
Protein name
Probable G-protein coupled receptor 125
Human protein sequence Database
Q8IWK6
Mouse protein sequence database
Q7TT36
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Epithelium,Eye,Liver,
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