Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Specificity
GP182 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008],
Function
caution:Was originally (PubMed:9367907) thought to be a receptor for adrenomedullin.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.,
Protein name
G-protein coupled receptor 182
Human protein sequence Database
O15218
Mouse protein sequence database
P43142
Rat protein sequence database
P31392
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.
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