Molecular weight (DA)
49kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Specificity
GPR61 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus. Also expressed in testis. Low expression in many other tissues.,
Protein name
Probable G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor)
Human protein sequence Database
Q9BZJ8
Mouse protein sequence database
Q8C010
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538). .
Tissue expression
Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level).
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