Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from human protein . at AA range: Internal
Specificity
RNAS4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013],
Function
function:This RNase has marked specificity towards the 3' side of uridine nucleotides.,similarity:Belongs to the pancreatic ribonuclease family.,
Protein name
Ribonuclease 4 (RNase 4) (EC 3.1.27.-)
Human protein sequence Database
P34096
Mouse protein sequence database
Q9JJH1
Rat protein sequence database
O55004
Cellular localization
Secreted.
Tissue expression
Fetal brain,Fetal liver,Pancreas,Placenta,Plasma,
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