Molecular weight (DA)
15kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
HBAZ Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009],
Function
function:The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac.,similarity:Belongs to the globin family.,subunit:Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in hemoglobin Portland-1.,tissue specificity:Red blood cells.,
Protein name
Hemoglobin subunit zeta (HBAZ) (Hemoglobin zeta chain) (Zeta-globin)
Human protein sequence Database
P02008
Mouse protein sequence database
P06467
Rat protein sequence database
Cellular localization
hemoglobin complex,extracellular exosome,
Tissue expression
Detected in fetal erythrocytes (at protein level).
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