Molecular weight (DA)
30kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
EGFL7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],
Function
function:Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.,similarity:Contains 1 EMI domain.,similarity:Contains 2 EGF-like domains.,
Gene Name
EGFL7 MEGF7 UNQ187/PRO1449
Protein name
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial
Human protein sequence Database
Q9UHF1
Mouse protein sequence database
Q9QXT5
Rat protein sequence database
Q6AZ60
Cellular localization
Secreted, extracellular space .
Tissue expression
Brain,Kidney,Ovary,Uterus,
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