Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
SLAF8 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008],
Function
function:May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,tissue specificity:Expressed in lymph node, spleen, thymus and bone marrow.,
Protein name
SLAM family member 8 (B-lymphocyte activator macrophage expressed) (BCM-like membrane protein) (CD antigen CD353)
Human protein sequence Database
Q9P0V8
Mouse protein sequence database
Q9D3G2
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Expressed in lymph node, spleen, thymus and bone marrow.
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