Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Specificity
R4RL1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,similarity:Belongs to the Nogo receptor family.,similarity:Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.,
Function
function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,similarity:Belongs to the Nogo receptor family.,similarity:Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.,
Gene Name
RTN4RL1 NGRH2 NGRL2
Protein name
Reticulon-4 receptor-like 1 (Nogo receptor-like 2) (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3)
Human protein sequence Database
Q86UN2
Mouse protein sequence database
Q8K0S5
Rat protein sequence database
Q80WD0
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft . Perikaryon . Cell projection . Localized to the surface of neurons, including axons. .
Tissue expression
Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.