Molecular weight (DA)
10kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
HRK Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
harakiri, BCL2 interacting protein(HRK) Homo sapiens This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
Function
domain:The BH3 motif is required for the induction of cell death.,function:Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).,
Protein name
Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5)
Human protein sequence Database
O00198
Mouse protein sequence database
P62816
Rat protein sequence database
P62817
Cellular localization
Membrane; Single-pass membrane protein. Mitochondrion.
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