Molecular weight (DA)
193kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ATL1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ADAMTS like 1(ADAMTSL1) Homo sapiens This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008],
Function
caution:Although strongly similar to members of the ADAMTS family it lacks the metalloprotease and disintegrin-like domains which are typical of that family.,mass spectrometry: PubMed:11805097,PTM:Disulfide bonds are present.,PTM:Glycosylated.,similarity:Contains 1 PLAC domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 TSP type-1 domains.,similarity:Contains 4 TSP type-1 domains.,subunit:Monomer.,tissue specificity:Expressed primarily in adult skeletal muscle.,
Gene Name
ADAMTSL1 ADAMTSR1 C9orf94 UNQ528/PRO1071
Protein name
ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1)
Human protein sequence Database
Q8N6G6
Mouse protein sequence database
Q8BLI0
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix .
Tissue expression
Expressed primarily in adult skeletal muscle.
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