Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ENOF1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins. [provided by RefSeq, Mar 2010],
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Divalent metal ions. Magnesium seems to be the preferred ion.,function:May regulate thymidylate synthase activity.,miscellaneous:Was initially (PubMed:8493092) identified as a gene coding for an antisense RNA to thymidylate synthase.,PTM:Could be sumoylated.,similarity:Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily.,
Gene Name
ENOSF1 RTS TYMSAS
Protein name
Mitochondrial enolase superfamily member 1 (EC 5.-.-.-) (Antisense RNA to thymidylate synthase) (rTS)
Fields
>>Fructose and mannose metabolism;>>Metabolic pathways
Human protein sequence Database
Q7L5Y1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Cervix carcinoma,Placenta,Trachea,
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