Molecular weight (DA)
53kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CLC14 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012],
Function
similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,
Gene Name
CLEC14A C14orf27 EGFR5 UNQ236/PRO269
Protein name
C-type lectin domain family 14 member A (Epidermal growth factor receptor 5) (EGFR-5)
Human protein sequence Database
Q86T13
Mouse protein sequence database
Q8VCP9
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Blood,Brain,
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