Molecular weight (DA)
178kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
NEST Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011],
Function
developmental stage:Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.,function:May play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell division.,similarity:Belongs to the intermediate filament family.,subunit:Interacts with FHOD3.,tissue specificity:CNS stem cells.,
Human protein sequence Database
P48681
Mouse protein sequence database
Q6P5H2
Rat protein sequence database
P21263
Cellular localization
cytoplasm,intermediate filament,extracellular matrix,intermediate filament cytoskeleton,
Tissue expression
CNS stem cells.
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