Molecular weight (DA)
20kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
APOD Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008],
Function
function:APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.,miscellaneous:APOD is primarily localized in HDL (60-65%), with most of the remainder in VHDL and only trace amounts in VLDL and LDL.,similarity:Belongs to the calycin superfamily. Lipocalin family.,subunit:Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2.,tissue specificity:Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.,
Protein name
Apolipoprotein D (Apo-D) (ApoD)
Human protein sequence Database
P05090
Mouse protein sequence database
P51910
Rat protein sequence database
P23593
Cellular localization
Secreted.
Tissue expression
Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.
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