Molecular weight (DA)
40kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TSSK1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174, potentially by autophosphorylation.,function:May be involved in a signaling pathway during male germ cell development or mature sperm function.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,
Gene Name
TSSK1B SPOGA1 SPOGA4 STK22A STK22D TSSK1 FKSG81
Protein name
Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)
Human protein sequence Database
Q9BXA7
Mouse protein sequence database
Q61241
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasmic vesicle, secretory vesicle, acrosome . Cell projection, cilium, flagellum . In spermatozoa, present in the sperm head and in the flagellum. .
Tissue expression
Testis-specific. Present in sperm (at protein level).
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