Molecular weight (DA)
53kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
B2L13 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
Function
alternative products:Experimental confirmation may be lacking for some isoforms,function:May promote the activation of caspase-3 and apoptosis.,similarity:Belongs to the Bcl-2 family.,subunit:Monomer.,tissue specificity:Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.,
Gene Name
BCL2L13 MIL1 CD003
Protein name
Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)
Fields
>>Mitophagy - animal;>>Legionellosis
Human protein sequence Database
Q9BXK5
Mouse protein sequence database
P59017
Rat protein sequence database
Cellular localization
[Isoform 2]: Mitochondrion membrane ; Single-pass membrane protein . Nucleus .; [Isoform 1]: Nucleus .
Tissue expression
Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
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