Molecular weight (DA)
93kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RASA2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Function
function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,
Gene Name
RASA2 GAP1M RASGAP
Protein name
Ras GTPase-activating protein 2 (GAP1m)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Viral carcinogenesis
Human protein sequence Database
Q15283
Mouse protein sequence database
P58069
Rat protein sequence database
Q63713
Cellular localization
Cytoplasm. Cytoplasm, perinuclear region.
Tissue expression
Blood,Brain,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车