Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
IN35 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Not yet known.,induction:By interferon gamma.,similarity:Belongs to the NMI family.,subcellular location:Nuclear following IFN treatment.,subunit:Homodimer. Also interacts with B-ATF.,tissue specificity:In a wide range of cell types, including fibroblasts, macrophages, and epithelial cells.,
Function
function:Not yet known.,induction:By interferon gamma.,similarity:Belongs to the NMI family.,subcellular location:Nuclear following IFN treatment.,subunit:Homodimer. Also interacts with B-ATF.,tissue specificity:In a wide range of cell types, including fibroblasts, macrophages, and epithelial cells.,
Protein name
Interferon-induced 35 kDa protein (IFP 35) (Ifi-35)
Human protein sequence Database
P80217
Mouse protein sequence database
Q9D8C4
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Secreted . Cytoplasmic IFI35 localizes in punctate granular structures (PubMed:10950963). Nuclear localization increased is stimulated by IFN-alpha (PubMed:8288566, PubMed:10950963). Extracelullar following secretion by macrophage (PubMed:29038465). .
Tissue expression
Expressed in a wide range of cell types, including fibroblasts, macrophages, and epithelial cells.
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