Molecular weight (DA)
36kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TSSC4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Function
similarity:Belongs to the TSSC4 family.,tissue specificity:Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.,
Protein name
Protein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)
Human protein sequence Database
Q9Y5U2
Mouse protein sequence database
Q9JHE7
Rat protein sequence database
Q5XIB1
Tissue expression
Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.
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