Molecular weight (DA)
49kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Specificity
IFRD1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],
Function
function:Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.,similarity:Belongs to the IFRD family.,subunit:Interacts with PSIP1/LEDGF.,tissue specificity:Expressed in a variety of tissues.,
Protein name
Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
Human protein sequence Database
O00458
Mouse protein sequence database
P19182
Rat protein sequence database
P20695
Cellular localization
nucleus,cytoplasm,
Tissue expression
Expressed in a variety of tissues.