Molecular weight (DA)
66kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Specificity
MAGD2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 MAGE domain.,tissue specificity:Widely expressed in normal tissues.,
Protein name
Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen)
Human protein sequence Database
Q9UNF1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
membrane,
Tissue expression
Widely expressed. In the developing and adult kidney, expressed in the thick ascending limb of the loop of Henle and the distal convoluted tubules outside the loop.
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