Molecular weight (DA)
57kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
UBP3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBP-type zinc finger.,tissue specificity:Expressed in all tissues examined, with strongest expression in pancreas.,
Function
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBP-type zinc finger.,tissue specificity:Expressed in all tissues examined, with strongest expression in pancreas.,
Protein name
Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)
Human protein sequence Database
Q9Y6I4
Mouse protein sequence database
Q91W36
Rat protein sequence database
Cellular localization
Nucleus . Localizes preferentially with monoubiquitinated H2A to chromatin.
Tissue expression
Expressed in all tissues examined, with strongest expression in pancreas.
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